top of page
Search
wittenberglab

Nate receives NSF CAREER Award!

We are thrilled to announce that Nate has received an NSF CAREER award for a proposal entitled, "CAREER: Investigating the Molecular Factors that Underlie Myelin-Associated Glycoprotein Binding." Myelin-associated glycoprotein (MAG) is a protein found on the inner myelin membrane, and it is one of a number of proteins that mediate the interaction between myelin and axons. MAG on myelin binds GD1a and GT1b gangliosides as well as Nogo receptor 1 (NgR1) on the axonal membrane.


This 5-year award (2021-2026) will support our research on how cholesterol and membrane phase separation can modulate the interactions between gangliosides and myelin-associated glycoprotein (MAG). Additionally, we will use a variety of analytical techniques to probe how the stoichiometry of the NgR1/p75/LINGO-1 receptor complex modulates the binding of MAG to NgR1.


This award will also support the development of an active learning-based upper level course on biosensors and bioanalytical chemistry, as well as teaching laboratory modules on lipid membrane-based biosensors.



184 views0 comments

Recent Posts

See All

Jennie Cawley wins TA Award!

On Tuesday December 1, the Lehigh Chemistry Department met virtually to announce the winners of the 2019-2020 Teaching Assistant (TA)...

Welcome to the new Wittenberg Lab website!

Welcome to our new home on the web! Have a look around and if you have any questions regarding our research please don't hesitate to ask....

Comments


bottom of page